Anti-CD38 therapy with daratumumab for relapsed/ refractory CD20-negative diffuse large B-Cell lymphoma

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Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common and one of the most aggressive subtypes of non-Hodgkin’s lymphomas. Front-line therapy consists of chemotherapy in combination with anti-CD20 monoclonal antibody rituximab. Relapses after rituximab-based regimen have poor prognosis and call for new treatment options. Immunohistochemistry analysis of relapsed DLBCL often reveal.

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Vockova, P., Svaton, M., Karolova, J., Pokorna, E., Vokurka, M., & Klener, P. (2020). Anti-CD38 therapy with daratumumab for relapsed/ refractory CD20-negative diffuse large B-Cell lymphoma. Folia Biologica (Czech Republic), 66(1), 17–23. https://doi.org/10.14712/fb2020066010017

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