Abstract
Growth differentiation factor 15 (GDF15) is a divergent member of the transforming growth factor-β (TGF-β) superfamily that has been associated with colorectal cancers (CRC). However, the role of GDF15 in the progression of CRC remains unknown. We demonstrated that GDF15 expression was higher in fresh CRC tissues than in adjacent normal tissues. Moreover, we found that GDF15 overexpression significantly facilitated cell viability, cell invasion and migration (p
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Zhang, Y., Wang, X., Zhang, M., Zhang, Z., Jiang, L., & Li, L. (2018). GPF15 promotes epithelial-to-mesenchymal transition in colorectal carcinoma. Artificial Cells, Nanomedicine and Biotechnology, 46(sup2), 652–658. https://doi.org/10.1080/21691401.2018.1466146
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