Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children

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Abstract

In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) human immunodeficiency virus (HIV)-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children. © The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved.

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Nicol, M. P., Spiers, K., Workman, L., Isaacs, W., Munro, J., Black, F., … Zar, H. J. (2013). Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children. Clinical Infectious Diseases, 57(3). https://doi.org/10.1093/cid/cit230

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