Animal Models Commonly Used to Study Quorum-Sensing Inhibitors

Abstract

Multiple animal models exist for the study of biofilm infections and their inhibitors in vivo. The infection models described in this chapter range from the simple nematode-killing and amoeba-plate-killing assays, to models with more rel- evance to human disease like the pulmonary and cellulitis infectionmodels in mice, the graft prosthesis, and the central venous catheter infectionmodels in rats, and the endocarditis and osteomyelitis infection models in rabbits.