A novel benzo[f][1,7]naphthyridine produced by streptomyces albogriseolus from mangrove sediments

Abstract

Mangrove Streptomyces represent a rich source of novel bioactive compounds in medicinal research. A novel alkaloid, named 1-N-methyl-3-methylamino-[N- butanoic acid-3'-(9'-methyl-8'-propen-7'-one)-amide]-benzo[f][1,7]naphthyridine- 2-one (1) was isolated from Streptomyces albogriseolus originating from mangrove sediments. The structure of compound 1 was elucidated by extensive spectroscopic data analyses and verified by the 13C-NMR calculation at the B3LYP/6-311+G(2d,p) level of theory. © 2010 by the authors; licensee MDPI, Basel, Switzerland.