Evaluation of the antimicrobial activity of crude extracts and isolated constituents from Chresta scapigera

Abstract

Crude extracts and eight isolated compounds from Chresta scapigera were evaluated for antibacterial and antifungal activities by the agar-well diffusion method. Twenty strains, including Gram-positive and Gramnegative bacteria and yeasts were used in the bioassay. Hexane extracts presented the best results while ethanol extracts did not indicate inhibition of the microbial growth. Amongst the evaluated compounds β-amyrin acetate, tiliroside and luteolin showed the strongest antimicrobial effect.