CJ-15,801, a novel antibiotic from a fungus, Seimatosporium sp.

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Abstract

A novel antibiotic, CJ-15,801 (I), was isolated from the fermentation broth of a fungus, Seimatosporium sp. CL28611. The structure was determined to be a pantothenic acid analog having an α,β-unsaturated carboxylic acid moiety by spectroscopic analyses. The compound inhibits the growth of multi-drug resistant (MDR) Staphylococcus aureus strains with MIC ranging from 6.25 to 50 μg/ml.

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Sugie, Y., Dekker, K. A., Hirai, H., Ichiba, T., Ishiguro, M., Shiomi, Y., … Kojima, Y. (2001). CJ-15,801, a novel antibiotic from a fungus, Seimatosporium sp. Journal of Antibiotics, 54(12), 1060–1065. https://doi.org/10.7164/antibiotics.54.1060

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