A comparison between Transcutaneous Bilirubin (TcB) and Total Serum Bilirubin (TSB) measurements in term neonates

Abstract

Introduction Transcutaneous Bilirubinometry (TcB) is a simple method for estimating bilirubin levels in neonates. This method is noninvasive, quick, and painless. We aimed to compare serum and cutaneous bilirubin measurements in term neonates. Materials and Methods In this descriptive cross-sectional study, 200 neonates with icter and birth weights of at least 2,500 grams were studied. TcB was measured using a bilirubinometer three times on the forehead and mean levels were calculated. Then, during the subsequent 30 minutes blood samples were obtained and sent to the laboratory for determining the Total Serum Bilirubin (TSB) levels. Results Of the 200 neonates, 124 (62%) were boys and 76 (38%) were girls, with an age range of 1-22 days. The mean±SD serum and cutaneous bilirubin levels were 18.75±5.38 and 17.85±4.46 mg/dl, respectively. A high correlation (r=0.89) was observed between TSB and TcB. The sensitivity and specificsity of cutaneous bilirubin measurement were 95.1% and 68%, respectively. Conclusion Because of its high sensitivity, TcB can be a suitable tool for predicting neonatal icter. However, it is not a suitable substitute for TSB measurement in neonates at a high risk of jaundice.