Structure elucidation of Sch 725674 from Aspergillus sp.

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Abstract

A new macrolide Sch725674 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was accomplished based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 32 μg/ml, respectively. © Japan Antibiotics Research Association.

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Yang, S. W., Chan, T. M., Terracciano, J., Loebenberg, D., Patel, M., & Chu, M. (2005). Structure elucidation of Sch 725674 from Aspergillus sp. Journal of Antibiotics, 58(8), 535–538. https://doi.org/10.1038/ja.2005.74

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