Arsenic trioxide induces growth inhibition and apoptosis in multiple myeloma cell lines. Reducing glutathione by ascorbic acid may enhance the efficacy of arsenic trioxide. Here vire report the results of an international multi-center study of arsenic trioxide in combination with ascorbic acid and dexamethasone as treatment for patients with advanced multiple myeloma.
CITATION STYLE
Wu, K. L., Beksac, M., Van Droogenbroeck, J., Amadori, S., Zweegman, S., & Sonneveld, P. (2006). Phase II multicenter study of arsenic trioxide, ascorbic acid and dexamethasone in patients with relapsed or refractory multiple myeloma. Haematologica, 91(12), 1722–1723.
Mendeley helps you to discover research relevant for your work.