Tracheal intubation in intellectually disabled patients: Clinical usefulness of remifentanil and sevoflurane without a muscle relaxant

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Abstract

ObjectiveTo compare two remifentanil doses (1 μg/kg and 2 μg/kg) in order to determine the preferred dose in intellectually disabled patients undergoing day care dental surgery under sevoflurane-induced general anaesthesia.MethodsPatients were randomly assigned to receive either 1 μg/kg (group 1) or 2 μg/kg (group 2) remifentanil; both groups received 8% sevoflurane anaesthesia induction. All other conditions were identical in both groups. Heart rate (HR), mean arterial pressure (MAP) and intubation conditions were assessed.ResultsA total of 27/30 (90.0%) patients in group 1 and 29/30 patients (96.7%) in group 2 had acceptable intubation conditions. Remifentanil administration resulted in significant reductions in HR compared with baseline levels, in both groups. There were no significant between-group differences in HR at any timepoint. MAP decreased significantly compared with baseline in group 2 only.ConclusionSuccessful tracheal intubation in intellectually disabled patients can be accomplished with a combination of 1 μg/kg or 2 μg/kg remifentanil and 8% sevoflurane anaesthesia induction, without the requirement for neuromuscular blocking drugs. © The Author(s) 2013.

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APA

Cagiran, E., Eyigor, C., Balcioglu, T., & Uyar, M. (2013). Tracheal intubation in intellectually disabled patients: Clinical usefulness of remifentanil and sevoflurane without a muscle relaxant. Journal of International Medical Research, 41(5), 1632–1638. https://doi.org/10.1177/0300060513497561

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