Polymeric membrane for verteporfirin purification

Abstract

Verteporfirin is the active substance of the medicine Visudyne (the basic form porphyrin of the medicine) approved and in use for ophthalmic diseases and tumor types. Because the informations from literature about degraded of this porphyrins are greatly reduced, we propose in this paper to separate the different degraded forms of this porphyrin by using polysulfone membrane polymer type. In this paper are presented some analytical results of verteporfirin before and after passing degraded form of the porphyrins over these membranes.