A unique atrial primary cardiac lymphoma mimicking myxoma presenting with embolic stroke: A case report

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Abstract

An immunocompetent 29-year-old male presented with an embolic stroke from an unusual primary cardiac lymphoma. The cardiac lesion consisted of a polypoid, left atrial, mural fibrin thrombus with anaplastic tumor cells lining the surface of the clot. Histologic, immunophenotypic, and molecular characterizations were consistent with a diagnosis of CD30+ large B-cell lymphoma with anaplastic cytology. While tumor emboli from invasive primary cardiac lymphomas have been reported, this noninvasive fibrin thrombus-associated lymphoma appears to be unique and previously unreported. © 2003 by The American Society of Hematology.

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Quigley, M. M., Schwartzman, E., Boswell, P. D., Christensen, R. L., Gleason, L. A., Sharpe, R. W., & D’Amato, T. A. (2003). A unique atrial primary cardiac lymphoma mimicking myxoma presenting with embolic stroke: A case report. Blood, 101(12), 4708–4710. https://doi.org/10.1182/blood-2002-08-2550

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