An alleviative effect of Lonicerae japonicae flos water extract against liver fibrogenesis in vitro and in vivo

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Abstract

Lonicerae japonicae (L. japonicae) flos is a medical and food homology herb. This study investigated the phenolic acid and flavonoid contents in L. japonicae flos water extract solution (LJWES) and the preventive effects of LJWES against liver fibrogenesis via FL83B cells and rats. LJWES contains many polyphenols, such as chlorogenic acid, morin, and epicatechin. LJWES increased cell viability and decreased cytotoxicity in thioacetamide (TAA)-treated FL83B cells (75 mM) (p

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Lin, Y. L., Wu, Y. H. S., Chao, M. Y., Yang, D. J., Liu, C. W., Tseng, J. K., & Chen, Y. C. (2024). An alleviative effect of Lonicerae japonicae flos water extract against liver fibrogenesis in vitro and in vivo. Environmental Toxicology, 39(5), 2881–2892. https://doi.org/10.1002/tox.24154

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