Is there an increased long-term risk of hypertension and renal impairment after Puumala virus-induced nephropathy?

Abstract

Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome, assumed to have a favorable prognosis. NE patients who manifested a higher glomerular filtration rate and mean systolic blood pressure, and more proteinuria, versus controls at 5 years of follow-up demonstrated no major abnormalities after 10 years. Antihypertensive treatment was, however, more common. Could NE predispose some patients to develop hypertension after all?