Comparison of the recovery characteristics of diazepam and midazolam

Abstract

A double-blind crossover comparison of efficacy and recovery from midazolam 5 mg and diazepam (in propylene glycol) 10 mg was undertaken in eight volunteer subjects. It was found that midazolam was significantly more potent in this dose ratio than diazepam. helping to explain the finding of previous studies that the recovery from midazolam and diazepam in a 1:2 dose ratio is comparable. © 1988 British Journal of Anaesthesia.