Two-dimensional, two-QTL scans

Abstract

Most complex traits are understood to be the result of the action of multiple genetic loci. Some loci may be linked, and the effect of some loci may depend on the genotype at others (epistasis). In this chapter, we undertake the first step in the direction of teasing apart the multiple linked or interacting QTL underlying a quantitative trait, by contemplating two-dimensional, two-QTL genome scans.