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The Influence of Human Growth Hormone (GH) and Thyroxine (T4) on the Differentiation of Adipose Tissue in the Fetus

Obesity Research (1993) 1(5) 345-356
DOI: 10.1002/j.1550-8528.1993.tb00012.x
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Abstract

Late term fetuses from genetically obese dams have slightly larger fat cells, greater adipose tissue lipoprotein lipase (LPL) activities, elevated levels of thyroid hormones, and depressed growth hormone (GH) levels when compared to fetuses from lean dams. We have investigated the influence of thyroid hormone and GH status per se on these and other adipose tissue traits by chronically treating hypophysectomized (hypox) fetuses (day 70) between day 90 and 105 of gestation with either thyroxine (T4) or human GH. Treatment with T4 decreased body weights (P

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Hausman, G. J., Wright, J. T., Latimer, A., Watson, R., & Martin, R. J. (1993). The Influence of Human Growth Hormone (GH) and Thyroxine (T4) on the Differentiation of Adipose Tissue in the Fetus. Obesity Research, 1(5), 345–356. https://doi.org/10.1002/j.1550-8528.1993.tb00012.x

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