A Meta-analysis of Ecotoxicological Hazard Data for Nanoplastics in Marine and Freshwater Systems

Abstract

There is emerging concern about the potential health and environmental impacts of nanoplastics in the environment. Information on exposure has been lacking, but a growing amount of ecotoxicological hazard data is now available, allowing a hazard assessment to be conducted for nanoplastics in freshwater and marine systems. Based on a critical evaluation of published studies and the construction of probabilistic species sensitivity distributions (PSSDs), we present a comprehensive, state-of-the-art understanding of nanoplastic ecotoxicity. Different freshwater and marine datasets were constructed based on different data quality levels, and for each of the datasets, PSSDs were built for both mass- and particle number-based concentrations. Predicted no-effect concentrations (PNECs) were then extracted from the PSSDs. We report PNECs at 99 and 72 μg L–1, respectively, for the freshwater and marine dataset after the removal of data measured in the presence of sodium azide (NaN3), which is considered to be a major interfering factor in the ecotoxicity testing of nanoplastics. By comparing the PNECs, we found that nanoplastics are less toxic than microplastics and many engineered nanomaterials. In addition, the effects of size and polymer type on toxicity were also statistically tested. We observed no significant difference in ecotoxicity for nanoplastics of different sizes, whereas polystyrene nanoplastics were significantly more toxic than all other tested nanoplastics. In conclusion, the results we present provide a comprehensive description of nanoplastic ecotoxicity based on current knowledge. The results constitute a fundamental step toward an environmental risk assessment for nanoplastics in freshwater and marine systems. Environ Toxicol Chem 2020;39:2588–2598. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.