Pediatric Achalasia in the Netherlands: Incidence, Clinical Course, and Quality of Life

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Abstract

Objective To assess incidence and clinical course of Dutch patients with Achalasia diagnosed before 18 years of age as well as their current symptoms and quality of life (QoL). Study design Retrospective medical chart review and a cross-sectional study assessing current clinical status using the Eckardt score and reflux disease questionnaire. General QoL was measured using Kidscreen-52 for patients <18 years of age or to 36-Item Short Form Health Survey for patients ≥18 years of age. Results Between 1990 and 2013, 87 children (mean age 11.4 ± 3.4 years, 60% male) diagnosed with Achalasia in the Netherlands were included. Mean incidence was 0.1/100 000/y (range 0.03-0.21). Initial treatment was pneumodilation (PD) in 68 (79%) patients and Heller myotomy (HM) in 18 (21%) patients. Retreatment was required more often after initial PD compared with initial HM (88% vs 22%; P

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Smits, M., Van Lennep, M., Vrijlandt, R., Benninga, M., Oors, J., Houwen, R., … Van Wijk, M. (2016). Pediatric Achalasia in the Netherlands: Incidence, Clinical Course, and Quality of Life. Journal of Pediatrics, 169, 110-115.e3. https://doi.org/10.1016/j.jpeds.2015.10.057

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