Use of PER977 to Reverse the Anticoagulant Effect of Edoxaban

  • Ansell J
  • Bakhru S
  • Laulicht B
  • et al.
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Abstract

Among 80 healthy persons who had received a single dose of edoxaban, the whole-blood clotting time was reduced significantly more rapidly in those who received the novel small molecule PER977 than in controls who were not given PER977.

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Ansell, J. E., Bakhru, S. H., Laulicht, B. E., Steiner, S. S., Grosso, M., Brown, K., … Costin, J. C. (2014). Use of PER977 to Reverse the Anticoagulant Effect of Edoxaban. New England Journal of Medicine, 371(22), 2141–2142. https://doi.org/10.1056/nejmc1411800

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