Acute syphilitic posterior placoid chorioretinitis

Abstract

Purpose To report two cases of acute syphilitic posterior placoid chorioretinitis (ASPPC). Cases A 53-year-old man presented with decreased vision in his right eye. There was a yellow-white lesion in the macular area. Serologic tests for syphilis were positive. Based on optical coherence tomography, fluorescein angiography and indocyanine green angiography findings we diagnosed ASPPC. After oral ampicillin treatment, the symptoms and ocular findings showed improvement. Another patient, a 54-year-old man, presented with decreased vision in his left eye. The optic disc in the left eye was hyper-emic and there was a yellow-white lesion in the macular area. Based on serologic tests and multimodal imaging, we diagnosed ASPPC. After intravenous penicillin administration, the symptoms and ocular findings showed improvement. Conclusion It is important to make a prompt and accurate differential diagnosis of ASPPC when yellowish-white lesions are present in the macular area.