CLINICOPATHOLOGICAL STUDY OF UTERINE LEIOMYOMAS IN HYSTERECTOMY SPECIMENS; A RETROSEPTIVE STUDY.

Abstract

Introduction: Leiomyomas are the commonly encountered benign uterine neoplasms in women of reproductive age group accounting for 5-20{\%}. We reported 100 cases of women who underwent who hysterectomy for uterine leiyomayomas which was diagnosed by clinically and sonologically. Methods: This is a retrospective study of 100 cases who underwent hysterectomy for uterine leiyomayomas which was diagnosed by clinically and sonologically between March 2016 to March 2017.Women who underwent hysterectomy with an indication other than for uterine leiyomayomas were excluded in the study. Data including age, parity, symptoms and clinical indication for hysterectomy were collected. Hysterectomy specimens clinically diagnosed as uterine leiomyomas were subjected to histopathological examination. Results: Age range of the patients with leiomyoma was 24-50years. Majority of the patients were between 41-50 years (51{\%} cases). Menorrhagia was the commonest symptom constituting 38{\%} cases and fibroid uterus was the most common clinical diagnosis provided (54{\%}). Most common location of leiomyoma's was intramural (66.66{\%}) followed by subserosal (20.37{\%}) 59{\%} leiomyoma's were single and 41{\%} were multiple. Degenerative changes were observed in 16.46{\%} cases, amongst which hyaline change was the most common (6.33{\%}). Histopathological patterns showed proliferative endometrium in 66{\%} and cystic granular hyperplasia in least of 2{\%} Cystic ovaries were seen in 11{\%} of the patients, adenomyosis in 19 {\%}. Conclusion: Fibromyoma is the most common benign tumor commonly affects the women of child-bearing age, mostly in the third decade. The most common presentation is menstrual disturbances. Intramural fibroid is the most common variety. The proliferative endometrium, followed by secretary endometrium was commonly reported.