Brønsted acid catalyzed asymmetric silylation of alcohols

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Abstract

Abstract We report a catalytic enantioselective desymmetrization of meso-1,2-diols by monosilylation using a chiral enantiopure Brønsted acid as catalyst and hexamethyldisilazane (HMDS) as silyl source.

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Hyodo, K., Gandhi, S., Van Gemmeren, M., & List, B. (2015). Brønsted acid catalyzed asymmetric silylation of alcohols. Synlett, 26(8), 1093–1095. https://doi.org/10.1055/s-0034-1380409

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