Three new natural antibacterial and antifungal dithiolopyrrolone antibiotics were isolated along with the known iso-butyropyrrothine and thiolutine from the fermentation broth of an actinomycete strain which was isolated from a saharian palm grove soil collected at Adrar, south Algeria. The strain was identified as Saccharothrix sp. The three new antibiotics exhibited broad antimicrobial activity against Gram-positive bacteria, yeasts and fungi in vitro.
CITATION STYLE
Lamari, L., Zitouni, A., Boudjella, H., Badji, B., Sabaou, N., Lebrihi, A., … Tillequin, F. (2002). New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. I. Taxonomy, fermentation, isolation and biological activities. Journal of Antibiotics, 55(8), 696–701. https://doi.org/10.7164/antibiotics.55.696
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