Successful management of stuttering priapism using home self-injections of the alpha-agonist metaraminol

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Abstract

Low-flow priapism can result in impotence if treatment is delayed, yet patients with recurrent priapism often suffer delay before therapy. We describe management of recurrent priapism using self-administered injections of intracavernosal metaraminol (Aramine™, Merck), a long-acting vasoconstricting amine that is considered safer than epinephrine. The patient injects as often as once daily using 5-10 mg of drug. Our patient reports rapid detumescence and has not required emergency room visits since starting injections. He denies complications. Treatment of priapism using metaraminol has been suggested in the hospital setting; however, this is the first report of successful home self-administration of the drug.

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McDonald, M., & Santucci, R. A. (2004). Successful management of stuttering priapism using home self-injections of the alpha-agonist metaraminol. International Braz J Urol, 30(2), 121–122. https://doi.org/10.1590/S1677-55382004000200007

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