Copper: Effects of deficiency and overload

152Citations
Citations of this article
114Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Copper is an essential trace metal that is required for the catalysis of several important cellular enzymes. However, since an excess of copper can also harm cells due to its potential to catalyze the generation of toxic reactive oxygen species, transport of copper and the cellular copper content are tightly regulated. This chapter summarizes the current knowledge on the importance of copper for cellular processes and on the mechanisms involved in cellular copper uptake, storage and export. In addition, we will give an overview on disturbances of copper homeostasis that are characterized by copper overload or copper deficiency or have been connected with neurodegenerative disorders. © Springer Science+Business Media Dordrecht 2013.

Cite

CITATION STYLE

APA

Scheiber, I., Dringen, R., & Mercer, J. F. B. (2013). Copper: Effects of deficiency and overload. Metal Ions in Life Sciences, 13, 359–387. https://doi.org/10.1007/978-94-007-7500-8_11

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free