Detection of T-cadherin expression in mouse embryos

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Abstract

The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.

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Rubina, K. A., Smutova, V. A., Semenova, M. L., Poliakov, A. A., Gerety, S., Wilkinson, D., … Tkachuk, V. A. (2015). Detection of T-cadherin expression in mouse embryos. Acta Naturae, 7(2), 87–94. https://doi.org/10.32607/20758251-2015-7-2-87-94

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