Chemical Compounds and Antioxidant Potential in Hot Water Extract of Cultivated Agarwood (Aquilaria malaccensis) Lamk Leaves

Abstract

Agarwood (Aquilaria malaccensis Lamk) leaves has potential as a source of antioxidants because in the hot water extract contains secondary metabolite compounds. This research aims to observe the chemical compounds and antioxidant potential in hot water extract of cultivated agarwood leaves. Agarwood leaves are processed into simplicia, and extracted with hot water. Several tests conducted in this research, including phytochemical screening in order to observe the chemical compounds in hot water extract of agarwood leaves; GC-MS test to observe the chemical constituents, and DPPH method to observe the antioxidant activity. Agarwood leaves hot water extract positively contained of flavonoid, triterpenoid, tannin and glycoside compounds. The identification result of agarwood leaves hot water extract using GC-MS test showed 9 compounds, they are Undecane, Benzene 1.3-dichloro-2-methoxy-, 1.alpha.- (Angeloxy)-6.beta-(isobutyroxy)-9-oxo-10.alpha.Hfuranoeremophilane, Methyl (6-Methyl-3-pyridazinyl) Ketone, 1-Heptyl-1H-(1,2,3)-triazole-N-{[2′-(hydroxyethoxy)ethylamino] ethyl}-4-carboxamide, 1-Heptyl-1H-(1,2,3)-triazole-N-{[2′-(hydroxyethoxy)ethylamino]ethyl}-4-carboxamide, Borane. [2-(dimethylphenylsilyl)-1-, ethyl-1-propenyl]diethyl-, (E)-, Hexadecanoic acid, methyl ester, and 1-Phenyl-5,5-dimethyl-4,6-dioxa-5-sila-8-nitrooct-1-ene. The antioxidant activity of agarwood leaves hot water extract is categorized as the very strong antioxidant activity.