Study on extraction process of curcuma zedoaria volatile oil and its effect on anticancer

Abstract

To investigate the extraction process of Curcuma zedoaria volatile oil and its effect on proliferation and apoptosis of human gastric cancer SGC-7901 cells. Orthogonal experimental method was used to analyze the effect of extraction factors-crushing degree, amount of added water and distillation time-on Curcuma zedoaria oil; MTT assay, PI staining and flow cytometry were used to study the effect of Curcuma zedoaria oil on human gastric cancer SGC-7901 cells. The crushing degree, amount of added water and distillation time all affect the extraction of Curcuma zedoaria oil, Curcuma zedoaria oil can inhibit human gastric cancer SGC-7901 cell proliferation and induce its apoptosis.