A Brief Chronological Overview of Buccal Film Formulations

Abstract

The bioadhesive buccal film drug delivery technology that increases the safety, effectiveness, and stability of active pharmaceutical ingredients is the main focus of the current article. The buccal film is cutting-edge technology since it offers a better way to maximise treatment effectiveness. The medications that are used to increase bioavailability and have a high first-pass metabolism are ideal for this drug delivery strategy. Rolling, hot-melt extrusion, solid dispersion, solvent casting, or semi-solid casting can all be used to make Bioadhesive Buccal Films (BBF). The solvent casting method is the most popular of them. Organoleptic valuation, thickness, transparency, surface pH, moisture content, tensile strength, per cent elongation, folding endurance, swelling assets, drug content, and in vitro dissolution tests are a few of the mechanical assets that are assessed for the BBF. A small amount of material on earlier work on BBF has been provided in the article. This article will be useful for quick references to prior BBF attempts and guidance on how to assess them.