New antibiotic pigments related to fusarubin from fusarium solani (mart.) sacc. i. fermentation, isolation, and antimicrobial activities

Abstract

A cholesterol-decomposing fungus, Fusarium solani (Mart.) Sacc. strain PP 96, was found to produce several different naphthaquinone pigments in a glycerol-mineral salts medium. Three novel compounds structurally related to fusarubin were isolated by chloroform extraction followed by silicic acid column chromatography and preparative thin-layer chromatography. The purified compounds were found to have relatively low activity against bacteria, yeasts and filamentous fungi. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.