Journal Article

A rapid method for the determination of therapeutic barbiturate levels in serum using gas-liquid chromatography

Clinica Chimica Acta (1973) 43(3) 327-332
DOI: 10.1016/0009-8981(73)90470-1
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Abstract

A rapid method for the detection and quantitation of low barbiturate concentrations in serum using gas-liquid chromatography is presented. 0.01 mg barbiturates per 100 ml serum can be determined using a 1-ml serum sample. A simple extraction is described with diethyl ether as solvent. Hexobarbitone is used as internal standard. © 1973.

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Williams, A. J., Jones, T. W. G., & Cooper, J. D. H. (1973). A rapid method for the determination of therapeutic barbiturate levels in serum using gas-liquid chromatography. Clinica Chimica Acta, 43(3), 327–332. https://doi.org/10.1016/0009-8981(73)90470-1

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