New paspalinine derivatives with antiinsectan activity from the sclerotia of Aspergillus nomius

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Abstract

14-Hydroxypaspalinine (3) and 14-(N,N-Dimethyl-L-valyloxy)paspaline (4) have been isolated from the sclerotia of Aspergillus nomius, and identified by analysis of 2D NMR data. Both compounds cause ca. 90% reduction in weight gain in assays against the corn earworm Helicoverpa zea at the 100 ppm (dry weight) dietary level. Paspaline causes no effect at this concentration. © 1993.

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Staub, G. M., Gloer, K. B., Gloer, J. B., Wicklow, D. T., & Dowd, P. F. (1993). New paspalinine derivatives with antiinsectan activity from the sclerotia of Aspergillus nomius. Tetrahedron Letters, 34(16), 2569–2572. https://doi.org/10.1016/S0040-4039(00)77627-1

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