Inspired by a zebrafish mutation, two recent studies by Creanga and colleagues (pp. 1312-1325) and Tukachinsky and colleagues have shed new light on the way in which lipidated Hedgehog proteins are secreted and released from expressing cells, suggesting a model for the sequential action of the Disp and Scube2 proteins in this process. © 2012 by Cold Spring Harbor Laboratory Press.
CITATION STYLE
Ingham, P. W. (2012). Zebrafish genetics gets the Scube on hedgehog secretion. Genes and Development, 26(22), 2468–2470. https://doi.org/10.1101/gad.207126.112
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