Stereocontrolled synthesis of optically active β-D-glucopyranosides of 3-hydroxy-7,8-didehydro-β-ionol

Abstract

A stereocontrolled synthesis of optically active β-D-glucopyranosides 1-4 of 3-hydroxy-7,8-didehydro-β-ionol utilizing an asymmetric transfer hydrogenation to α,β-acetylenic ketones catalyzed by chiral ruthenium complexes as the key step is described.