Single-dose cefotaxime intramuscularly cures gonococcal ophthalmia neonatorum

Abstract

Nine neonates with culture proved gonococcal ophthalmia neonatorum were treated with a single intramuscular injection of 100 mg/kg of cefotaxime without topical antibiotic therapy. Five of the nine strains were penicillinase- producing Neisseria gonorrhoeae. All nine cases were clinically and microbiologically cured, and no side effects were observed.