ADVERSE DRUG REACTIONS: A COMPREHENSIVE REVIEW

Abstract

Adverse drug reactions are the undesirable unintended response of the drug which occurs at the doses normally used for the diagnosis, prophylaxis and treatment of the patient. ADR is the harmful effect other than desirable or expected which can vary from desirable from mild to severe reaction, even sometimes responsible for causing considerable morbidity and mortality. The reasons include overdose, polypharmacy, diseased condition etc. to name few among them. The increased ADR rate is highly alarming and thus requires proper monitoring and reporting of ADR to the concerned regulatory authorities. In this review we try to cover different aspects of adverse drug reactions like its types, factors affecting ADR, reasons for increasing rate of ADR, preventive measures and also the monitoring and reporting of ADR.