A Review of the Sustainability, Chemical Composition, Bioactive Compounds, Antioxidant and Antidiabetic Activity, Neuroprotective Properties, and Health Benefits of Microalgae

Abstract

Microalgae have emerged as a valuable source of essential nutrients and bioactive compounds, such as proteins, polyphenols, and polysaccharides, which are critical for overall health. Recent research has demonstrated the therapeutic potential of microalgae in addressing a variety of health conditions, including inflammation, oxidative stress, Type 2 diabetes mellitus (T2DM), and neurological disorders. The aim of this paper is to investigate the chemical composition, nutritional value, and biological properties of microalgae. Relevant information was gathered through a comprehensive search of scientific databases, including PubMed, Science Direct, Google Scholar, and the Cochrane Library. Key microalgal strains such as Spirulina platensis, Chlorella vulgaris, Haematococcus pluvialis, and Dunaliella salina have shown notable health-promoting properties. For instance, Spirulina platensis is rich in proteins, vitamins, and polyunsaturated fatty acids, while Chlorella vulgaris offers significant levels of chlorophyll and carotenoids. Haematococcus pluvialis is recognized for its high astaxanthin content and Dunaliella salina for its beta-carotene content. These microalgae strains have demonstrated beneficial effects in managing type 2 diabetes mellitus, alleviating oxidative stress, and offering neuroprotective potential. This paper provides an overview of microalgae’s nutritional composition, their medicinal properties, and their promising role in treating chronic diseases, with a particular focus on their applications in antidiabetic and neuroprotective therapies.