Avaliação clínica e micológica de onicomicose em pacientes brasileiros com HIV/AIDS

Abstract

Introduction: Onychomycosis is common in immunocompromised patients, but emerging species have been verified, thereby modifying the epidemiological profile of this mycosis. Thus, the aim of this study was to evaluate clinical and mycological profile of onychomycosis among HIV/AIDS patients. Methods: Clinical samples were collected and processed for direct examination, and cultures were maintained at a temperature of 30°C and 37°C for 15 days. Results: Out of 100 patients, 32 had onychomycosis. Te etiological agents isolated were Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondii, Trichophyton rubrum, T. mentagrophytes, Fusarium solani, Scytalidium hialinum, S. japonicum, Aspergillus niger, Cylindrocarpon destructans and Phialophora reptans. Conclusions: Onychomycosis in HIV/AIDS patients presents various clinical manifestations and may be caused by emerging fungi. Te peculiarities presented by different fungal agents justify the need for identification to species level, with the purpose of guiding better therapeutic approaches and minimizing these patients' exposure to conditions presenting a risk of disseminated infection.