A simple, convenient and effective method for the synthesis of dibenz(b,f) 1,4-oxazepines(cr); a new generation riot control agent and its analogues

Abstract

A new synthetic route has been developed for the synthesis of seven membered heterocyclic ring dibenz (b, f) 1,4-oxazepine (CR) starting with condensation of o-aminophenol and o-chlorobenzaldehyde followed by salt formation and cyclisation in DMSO at 120°C. The method has been extended for the preparation of other substituted dibenzoxazepines.