Impacto da vacinação contra rotavírus no Brasil

Abstract

Study Design: Sistematic Review of literature. Aims: In this work, national studies were reviewed in the literature by key words infection, hospitalization, mortality, and rotavirus genotypes during pre e postvaccinal periods. Methodology: Pubmed and Scielo databases were searched for associated descriptors: rotavirus, Brazil and infection; rotavirus, Brazil and hospitalized; rotavirus, Brazil and mortality; rotavirus, Brazil and genotypes. Results: Results appointed for significant reduction of infection (7.4-77%), hospitalization (12.3-55.4%), and mortality (22-50%), besides rotavirus gastroenteritis continue to be an important disease. After introduction to immunization practices, great changes of rotavirus genotypes were described, with G2P4 predominance in substitution to G1P8. Conclusion: The started of rotavirus vaccination results important impact of rotaviruses infection, concomitant to alteration of rotavirus genotype circulation implicating to need for molecular surveillance to change of rotavirus genotypes compounds in vaccine to efficacy guaranteed.