NDM-8 metallo-βlactamase in a multidrug-resistant escherichia coli strain isolated in Nepal

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Abstract

A novel metallo-βlactamase, NDM-8, was identified in a multidrug-resistant Escherichia coli isolate, IOMTU11 (NCGM37), obtained from the respiratory tract of a patient in Nepal. The amino acid sequence of NDM-8 has substitutions at positions 130 (Asp to Gly) and 154 (Met to Leu) compared with NDM-1. NDM-8 showed enzymatic activities against βlactams similar to those of NDM-1. Copyright © 2013, American Society for Microbiology. All Rights Reserved.

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Tada, T., Miyoshi-Akiyama, T., Dahal, R. K., Sah, M. K., Ohara, H., Kirikae, T., & Pokhrel, B. M. (2013). NDM-8 metallo-βlactamase in a multidrug-resistant escherichia coli strain isolated in Nepal. Antimicrobial Agents and Chemotherapy, 57(5), 2394–2396. https://doi.org/10.1128/AAC.02553-12

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