p53 mutants: The Achilles' heel of human cancers?

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Abstract

Recent scientific discoveries have thrust mutants of the tumor suppressor protein p53 into the forefront of the war on cancer, and hold out eventual hope for a small molecule drug that will be useful in treating human cancers with mutant p53 protein.

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Brachmann, R. K. (2004). p53 mutants: The Achilles’ heel of human cancers? Cell Cycle. Taylor and Francis Inc. https://doi.org/10.4161/cc.3.8.1076

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