Autogenous vaccine therapy for condyloma acuminatum. A double-blind controlled study

Abstract

In an attempt to substantiate claims that autogenous vaccine is an effective form of immunotherapy for condyloma acuminatum, a double-blind cross-over study was carried out on 34 patients, in which autogenous wart vaccine was compared with a placebo vaccine identically prepared from each patient's own normal skin. It was found that the duration of disease was an important determinant of curability in patients with condylomata acuminata (P < 0.001) and that when this factor was taken into account autogenous wart vaccine was not significantly more effective than the placebo (P = 0.43).