Histology of Platelet-Plasma Clots from Normal Subjects and Patients with Abnormal Coagulation

Abstract

Microscopic study of platelet-plasma clots has demonstrated certain structural defects in clots from patients with diseases manifest by abnormal coagulation. Abnormally formed clots were found from patients with polycythemia vera, macroglobulinemia, Christmas disease, AC-globulin deficiency and fibrinolytic syndrome. Some of the problems imposed by the method are discussed.