To respond or not to respond to CD40 agonism: That is the prediction

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Abstract

In the context of the clinical development of a CD40-stimulatory monoclonal antibody for the treatment of B-cell cancers, a tumor mRNA-based gene signature reflecting CD40 signaling pathway activation status was identified that could be used to predict responding and non-responding patients with diffuse large B cell lymphoma (DLBCL). © 2012 Landes Bioscience.

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Shi, X., & Dornan, D. (2012). To respond or not to respond to CD40 agonism: That is the prediction. OncoImmunology. https://doi.org/10.4161/onci.1.1.17827

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