New schemes for the synthesis of glycolipid oligosaccharide chains

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Abstract

The driving force for the constant improvement and development of synthetic methodologies in carbohydrate chemistry is the importance of natural oligosaccharide chains in numerous biological phenomena such as cell growth, differentiation, adhesion, etc. Here, we report our syntheses of the spacer-armed oligosaccharides of sialylated lacto- and neolacto-, globo-, ganglia-, and sulfoglucuronylparagloboside-series, which include new rationally designed synthetic blocks, efficient solutions for the stereoselective construction of glycosidic bonds, and novel protection group strategies.

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Nifantiev, N. E., Sherman, A. A., Yudina, O. N., Cheshev, P. E., Tsvetkov, Y. E., Khatuntseva, E. A., … Shashkov, A. S. (2004). New schemes for the synthesis of glycolipid oligosaccharide chains. In Pure and Applied Chemistry (Vol. 76, pp. 1705–1714). Walter de Gruyter GmbH. https://doi.org/10.1351/pac200476091705

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