Delayed pseudopregnancy in the mouse

Abstract

Treatment of female mice with bromocriptine on Day 1 or 3 of pregnancy induced many of the females to return to oestrus. The incidence of extended cycles (7-10 days) and pseudopregnancies following this return to oestrus was significantly higher than in unmated control females. These observations are consistent with the existence of a 'mnemonic' component of the luteotrophic system in the mouse.