Synthesis of new sulphanilamide based schiff base nickel complexes with study of its antibacterial activity and nanoparticle synthesis

Abstract

Schiff base contains the Azomethine group prepared by reaction of the carbonyl group and amine group. In this project, Schiff bases of sulphanilamide on the treatment of imidazole-2-carboxaldehyde and Dehydroacetic acid have been synthesized. Further, their Nickel complexes have been synthesized. They were characterized by IR, Mass, NMR, UV-Vis spectra and found to have square planar geometry. They were screened with few bacteria and found to have good antibacterial activity against gram-negative bacteria. Further, NiO nanoparticles were synthesized by thermal decomposition of the above synthesized Nickel Schiff base complexes and found to have 93-98 nm particle size.